Opportunity Information: Apply for RFA FD 22 019

This opportunity is a Food and Drug Administration (FDA) cooperative agreement supplement focused on strengthening how state and federally recognized tribal partners respond when manufactured food samples raise compliance concerns. It is framed as a "revision application," meaning it is intended as an expansion or supplement tied to existing work under the Laboratory Flexible Funding Model (LFFM). The central public health aim is to help grantees build the practical capacity and capability to take appropriate follow-up actions after laboratory testing identifies samples that are confirmed violative or potentially violative. In plain terms, the program is meant to close the gap between finding a problem in the lab and taking effective regulatory or enforcement steps to protect consumers.

A core theme of the award is integration. The FDA is looking for tighter coordination between laboratory functions (sampling, testing, confirmation, data reporting) and regulatory functions (compliance decisions, enforcement actions, communications, and product control measures). By expanding into compliance and enforcement, the program supports a more complete system that can prevent problems before they spread, identify hazards faster, contain issues once they are detected, and remove adulterated, contaminated, or mislabeled manufactured food products from the marketplace when needed. The emphasis is not just on generating test results, but on ensuring those results lead to timely, appropriate action that reduces risk to the public.

Administratively, this is a discretionary funding opportunity using a cooperative agreement mechanism (U18). A cooperative agreement typically implies substantial involvement from the FDA compared with a standard grant, such as ongoing collaboration, technical input, and alignment with federal priorities and program expectations. Clinical trials are explicitly not allowed, so funded activities should be operational, programmatic, and regulatory in nature rather than clinical research.

Eligible applicants are limited to state governments and federally recognized Native American tribal governments. The funding opportunity is issued by the Department of Health and Human Services (HHS), specifically the FDA, and it sits within the broad activity area of agriculture, consumer protection, and food and nutrition. The opportunity is identified by Funding Opportunity Number RFA-FD-22-019 and is associated with CFDA number 93.103.

In terms of scale and competition, the program anticipated up to 15 awards, with an award ceiling of $100,000 per award. The posting indicates a creation date of January 26, 2022, and an original closing date of April 4, 2022. Overall, the supplement is designed to help participating jurisdictions build a more end-to-end manufactured food protection system where lab findings reliably trigger well-coordinated compliance and enforcement responses, ultimately improving the prevention and control of unsafe or inaccurately labeled food products in commerce.

  • The Department of Health and Human Services, Food and Drug Administration in the agriculture, consumer protection, food and nutrition sector is offering a public funding opportunity titled "Revision Applications - Manufactured Food Flexible Funding Model Compliance and Enforcement Expansion Supplement (U18) (Clinical Trials Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
  • This funding opportunity was created on Jan 26, 2022.
  • Applicants must submit their applications by Apr 04, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • The number of recipients for this funding is limited to 15 candidate(s).
  • Eligible applicants include: State governments, Native American tribal governments (Federally recognized).
Apply for RFA FD 22 019

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Retail Food Safety Regulatory Association Collaboration (U18) (Clinical Trial Not Allowed) Apply for RFA FD 22 008

Funding Number: RFA FD 22 008
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $1,000,000
Renewal - Native American Tribes Outreach, Education, and Training to Enhance Food Safety and FSMA Compliance (U01) Clinical Trial Not Allowed Apply for RFA FD 22 025

Funding Number: RFA FD 22 025
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $500,000
Renewal- Local Food Producer Outreach, Education, and Training to Enhance Food Safety and FDA Food Safety Modernization Act (FSMA) Compliance (U01) Clinical Trail Not Allowed Apply for RFA FD 22 024

Funding Number: RFA FD 22 024
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $1,000,000
Funding Opportunity Title Innovation Award: Minority Health and Health Equity (U01) Clinical Trials Optional Apply for RFA FD 22 005

Funding Number: RFA FD 22 005
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
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OMHHE Educational Funding Opportunity: Expanding education on skin lightening products (U01) Clinical Trials Optional Apply for RFA FD 22 020

Funding Number: RFA FD 22 020
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $250,000
Building Research Capacity in Global Tobacco Product Regulation Program (U18) Clinical Trials Not Allowed Apply for RFA FD 23 003

Funding Number: RFA FD 23 003
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $400,000
Cooperative Agreement to Support the Food and Agriculture Organization (FAO) (U01) Clinical Trials Not Allowed Apply for RFA FD 23 020

Funding Number: RFA FD 23 020
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $750,000
Flexible Funding Model-Infrastructure Development and Maintenance for State Manufactured Food Regulatory Programs (U2F) Clinical Trials Not Allowed Apply for RFA FD 23 027

Funding Number: RFA FD 23 027
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $565,000
Development and Maintenance of Human and Animal Food Rapid Response Teams (U2F) Clinical Trials Not Allowed Apply for RFA FD 23 019

Funding Number: RFA FD 23 019
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $360,000
Renewal-Native American Tribes Outreach, Education, and Training to Enhance Food Safety and FSMA Compliance (U01) Clinical Trial Not Allowed Apply for RFA FD 23 032

Funding Number: RFA FD 23 032
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $500,000
Renewal-Local Food Producer Outreach, Education and Training to Enhance Food Safety and FDA Food Safety Modernization Act (FSMA) Compliance (U01) Clinical Trial Not Allowed Apply for RFA FD 23 031

Funding Number: RFA FD 23 031
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $1,000,000
Vet-LIRN Capacity-Building Project and Equipment Grants (U18) Apply for PAR 23 202

Funding Number: PAR 23 202
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $2,500,000
Cooperative Agreement to Support an Evidence-Based Clinical Practice Guideline for the Management of Laparoscopic Abdominal Surgeries (U01) Clinical Trials Not Allowed Apply for RFA FD 23 035

Funding Number: RFA FD 23 035
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $2,000,000
Cooperative Agreement to Support an Evidence-Based Clinical Practice Guideline for the Management of Acute Low Back Pain (U01) Clinical Trials Not Allowed Apply for RFA FD 23 034

Funding Number: RFA FD 23 034
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $2,000,000
Data Standards for Tobacco Research and Scientific Review Phase 2 Apply for RFA FD 24 001

Funding Number: RFA FD 24 001
Agency: Department of Health and Human Services, Food and Drug Administration
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Manufacturing Sector Research Initiative Apply for RFA FD 17 009

Funding Number: RFA FD 17 009
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
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Cooperative Agreement to Support the Joint Institute for Food Safety and Applied Nutrition, JIFSAN (U19) Apply for RFA FD 17 003

Funding Number: RFA FD 17 003
Agency: Food and Drug Administration
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National Laboratory Curriculum Framework Development Apply for RFA FD 17 012

Funding Number: RFA FD 17 012
Agency: Food and Drug Administration
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Developing Biomarkers for Trastuzumab-induced Cardiotoxicity Apply for RFA FD 17 006

Funding Number: RFA FD 17 006
Agency: Food and Drug Administration
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CVM Vet-LIRN Veterinary Diagnostic Laboratory Program (U18) Clinical Trials Apply for PAR 22 063

Funding Number: PAR 22 063
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